Bax

Mouse anti-human: monoclonal antibody Applicable tissue: paraffin section

Clone number : 2D2 Pre-processing: Hot fix ( EDTA ）

Positive site: cytoplasm Positive Control : kidney

Registration No.: Yuezhong Equipment 20200109 Number

Bax is Bcl-2 The molecular weight of the protein is 21kDa .and Bcl-2 The difference is, Bax It is a factor that promotes cell apoptosis. Under normal circumstances, Bax Can be used with Bcl-2 and Bcl-XL Form heterodimers. It can prevent cell apoptosis. Its role in promoting apoptosis may be through Bax Overexpression can lead to Bax Homodimer formation, inducing Caspase The release is achieved, Caspase Can activate cytochrome from mitochondria C This antibody is mainly used in the research of follicular lymphoma and cell apoptosis.